Over 250 scientific publications pay homage to this name phrase, when queried on PubMed.gov – a free online search database of biomedical literature developed and maintained by National Center for Biotechnology Information (NCBI)
In fact, at the turn of the century, we saw the first publication with “Molecular Portraits” in its title in an issue of the high ranking journal of Nature. Generally, such publications refer to “Molecular Portraits” when they repot findings that uncover a complexity in the biology of the disease of their scientific interest.
Notably, reference to complexity is made to the molecular biology of the disease. Over 250 publications unpack this molecular complexity in Oncology (aka – the study of Cancer).
Unpacking and developing signatures of this complexity as molecular biomarker signatures is at the forefront of Precision Medicine and Personalized Health. It, therefore, plays an important role in discovery and development of drug, treatment response and staging of diseases.
Less than 10 years ago, MSigDb, a molecular signature database on well annotated gene sets was published in Bioinformatics
Read here about Dr. Anthony Fauci and colleagues message to do more work in immunology with molecular imaging.
TMP’s tribute to geography and astronomy- a precedence to transform human health
A subset of the 250+ publications unpack this complexity of molecular biology in diseases with added information on the geography. This subset unpacks by addressing the question – WHERE is this molecular complexity taking place? What are its co-ordinates and over time, in response to treatment, across the stages of disease?
Signatures with this added geographical information is unprecedented. More importantly, the high dimensional and multidimensional data it generates demands precedence on artificial intelligence. Or does it?
“The Molecular Portraits” pays tribute to this precedence with relevant articles with intent to engage novice and experts alike in the field of spatial molecular imaging and digital pathology.
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